The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2025

Filed:

Dec. 04, 2024
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Lan-Ying Qin, Plainsboro, NJ (US);

Zheming Ruan, Dayton, NJ (US);

Ashok Vinayak Purandare, Pennington, NJ (US);

Emily Charlotte Cherney, Newtown, PA (US);

James Aaron Balog, Lambertville, NJ (US);

Arvind Mathur, Bridgewater, NJ (US);

Samuel J. Bonacorsi, Flemington, NJ (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 413/14 (2006.01); A61K 31/4545 (2006.01); A61K 45/06 (2006.01); C07B 59/00 (2006.01);
U.S. Cl.
CPC ...
C07D 413/14 (2013.01); A61K 31/4545 (2013.01); A61K 45/06 (2013.01); C07B 59/002 (2013.01);
Abstract

Disclosed are compounds of Formula (I): or stereoisomers, tautomers, or salts thereof, wherein each R is independently H or D. Also disclosed are methods of using such compounds to decrease the levels of IKZF1-4 proteins; and pharmaceutical compositions comprising the compound. The compounds are useful in the treatment of viral infections and proliferative disorders, such as cancer.


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