The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Sep. 30, 2024
Uniwersytet Jagiellonski, Cracow, PL;
Warszawski Uniwersytet Medyczny, Warsaw, PL;
Krzysztof Kaminski, Cracow, PL;
Michal Abram, Cracow, PL;
Marcin Jakubiec, Wilkowice, PL;
Anna Rapacz, Cracow, PL;
Szczepan Mogilski, Labowa, PL;
Gniewomir Latacz, Wolbrom, PL;
Marta Struga, Milanowek, PL;
Uniwersytet Jagiellonski, Cracow, PL;
Warszawski Uniwersytet Medyczny, Cracow, PL;
Abstract
2-(2,5-dioxopyrrolidin-1-yl)propanamide and 2-(2-oxopyrrolidin-1-yl)propanamide derivatives with R-configuration at the stereogenic center are disclosed, showing broad-spectrum protective activity in animal models of epileptic seizures, pain, depression and anxiety that are simultaneously devoid of undesirable sedative effects. Additionally, the disclosed derivatives have neuroprotective effects in the in vitro and in vivo studies.