The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2025

Filed:

Oct. 18, 2022
Applicant:

Jenkem Technology Co., Ltd. (Tianjin), Tianjin, CN;

Inventors:

Zhen Wei, Tianjin, CN;

Meina Lin, Tianjin, CN;

Xuan Zhao, Tianjin, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 59/305 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); C07C 31/20 (2006.01); C07C 31/22 (2006.01); C07C 31/24 (2006.01); C07C 59/31 (2006.01); C07C 235/08 (2006.01); C07D 303/12 (2006.01);
U.S. Cl.
CPC ...
C07C 59/305 (2013.01); A61K 47/60 (2017.08); C07C 31/202 (2013.01); C07D 303/12 (2013.01);
Abstract

Being used for drug modification, the multi-arm single molecular weight polyethylene glycol active derivative provided herein can effectively improve the solubility, stability, and immunogenicity of the drugs, improve the absorption of the drugs in vivo, prolong the half-life of the drugs, and increase bioavailability, enhance efficacy, and reduce toxic and side effects of the drugs. A gel formed from the multi-arm single molecular weight polyethylene glycol active derivative provided herein can be used for the preparation of controlled release drugs so as to prolong the action time of the drugs, thereby reducing the number of administrations and improving patient compliance.


Find Patent Forward Citations

Loading…