The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 17, 2025

Filed:

Sep. 18, 2019
Applicant:

Reva Medical, Llc, San Diego, CA (US);

Inventors:

Durgadas Bolikal, San Diego, CA (US);

Lioubov Kabalnova, San Diego, CA (US);

Ruth Sosa, San Diego, CA (US);

Ernest G. Baluca, San Diego, CA (US);

Jessica Earley, San Diego, CA (US);

Joann Yao, San Diego, CA (US);

Elizabeth Nesseler, San Diego, CA (US);

Assignee:

REVA Medical, LLC, San Diego, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/337 (2006.01); A61K 31/704 (2006.01); A61L 24/00 (2006.01); A61L 24/06 (2006.01);
U.S. Cl.
CPC ...
A61L 24/001 (2013.01); A61K 31/337 (2013.01); A61K 31/704 (2013.01); A61L 24/0015 (2013.01); A61L 24/0036 (2013.01); A61L 24/06 (2013.01); A61L 2300/216 (2013.01); A61L 2300/232 (2013.01); A61L 2300/62 (2013.01); A61L 2430/36 (2013.01);
Abstract

Methods, copolymer materials and devices are provided for embolic arterial interventions (embolization therapy or embolotherapy). More particularly, radiopaque, bioresorbable spherical microparticles for embolization or vascular occlusion therapies, comprising copolymers of iodine-containing, halogenated phenyl-containing units, such as iodinated desaminotyrosine derivatives, and rubbery components, such as polyethylene glycol (PEG), polycaprolactone (PCL), polytetramethylene oxide (PTMO) or polytrimethylene carbonate (PTMC), are provided. The provided microbeads may further contain, or be coated with, therapeutic agents such as paclitaxel, for targeted delivery of the therapeutics.


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