The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 17, 2025
Filed:
Jan. 29, 2021
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Feng Zhang, Pflugerville, TX (US);
Abbe Miller, Austin, TX (US);
Siyuan Huang, Austin, TX (US);
Robert O. Williams, Iii, Austin, TX (US);
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/4184 (2006.01); A61J 3/10 (2006.01); A61K 9/16 (2006.01); A61K 9/20 (2006.01); A61K 31/192 (2006.01); B29C 48/00 (2019.01); C08L 1/02 (2006.01); C08L 1/28 (2006.01); B29K 105/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4184 (2013.01); A61J 3/10 (2013.01); A61K 9/1635 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2095 (2013.01); A61K 31/192 (2013.01); C08L 1/02 (2013.01); C08L 1/284 (2013.01); B29C 48/023 (2019.02); B29K 2105/0035 (2013.01); B29K 2995/0059 (2013.01);
Abstract
Compositions and methods of preparing amorphous drug formulations through hot melt extrusion which result in decreased decomposition of the desired drug are provided herein. Also provided are methods and compositions which further comprise a pharmaceutically acceptable thermoplastic polymer. In some embodiments, these compositions comprise a therapeutically active agent which is only sparingly soluble in water.