The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2025

Filed:

Jul. 17, 2019
Applicant:

Novartis Ag, Basel, CH;

Inventors:

Agostino Cirillo, Basel, CH;

Hilmar Ebersbach, Wallisellen, CH;

Boerje Haraldsson, Basel, CH;

Thomas Huber, Allschwil, CH;

Guido Junge, Basel, CH;

Regina Link, Münchenstein, CH;

Max Warncke, Basel, CH;

Chao Zou, Allschwil, CH;

Assignee:

NOVARTIS AG, Basel, CH;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/14 (2006.01); A61K 38/46 (2006.01); A61K 45/06 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C12N 9/14 (2013.01); A61K 38/465 (2013.01); A61K 45/06 (2013.01); A61K 38/00 (2013.01); C12Y 306/01005 (2013.01);
Abstract

Provided herein are solubilized apyrase polypeptides, nucleotides encoding such solubilized apyrase polypeptides, pharmaceutical compositions containing such solubilized apyrase polypeptides, therapeutic uses of such solubilized apyrase polypeptides. Also provided herein are methods useful for preventing or treating tissue damage, e.g., by administering a solubilized apyrase polypeptide or pharmaceutical composition thereof, and methods for producing such solubilized apyrase polypeptides.


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