The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Dec. 17, 2021
Regeneron Pharmaceuticals, Inc., Tarrytown, NY (US);
Michael E. Dunn, Montvale, NJ (US);
Lori C. Morton, Chappaqua, NY (US);
Neil Stahl, Carmel, NY (US);
Tammy T. Huang, Cross River, NY (US);
Ishita Chatterjee, Nanuet, NY (US);
Vishal Kamat, Northbridge, MA (US);
Ashique Rafique, Yonkers, NY (US);
REGENERON PHARMACEUTICALS, INC., Tarrytown, NY (US);
Abstract
The present disclosure provides novel immunoglobulin proteins that bind to a human natriuretic peptide receptor 1 (NPR1) agonist, preferably an anti-NPR1 antibody. In certain embodiments, the proteins of the disclosure comprise at least one immunoglobulin variable domain that binds to an anti-NPR1 antibody. In certain embodiments, the proteins of the disclosure are useful in blocking and/or reversing the effect of an administered anti-NPR1 antibody. In certain embodiments, the antigen-binding proteins are useful for effective management of blood pressure and hemodynamics in humans.