The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Jan. 15, 2020
Altor Bioscience, Llc, Miramar, FL (US);
The Usa, As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Peter Rhode, Miami, FL (US);
Mark Connors, Bethesda, MD (US);
Stephen Migueles, Washington, DC (US);
Altor Bioscience LLC, Culver City, CA (US);
The USA, as represented by the Secretary, Dept. of Health and Human Services, Bethesda, MD (US);
Abstract
Engineered TCR molecules specific to retroviral peptide/HLA complexes guide direct killing and/or enable robust immune responses against HIV infected cells. In a first aspect, a TCR fusion polypeptide comprises a TCR variable alpha (Vα) domain, a TCR variable beta domain (Vβ) and a TCR constant region domain (C), wherein the TCR fusion polypeptide is specific for HIV peptides.