The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2025

Filed:

Sep. 15, 2019
Applicant:

National University Corporation, Iwate University, Morioka, JP;

Inventors:

Hiroshi Tomita, Morioka, JP;

Eriko Sugano, Morioka, JP;

Kitako Tabata, Morioka, JP;

Yoshito Watanabe, Morioka, JP;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/17 (2006.01); A61K 48/00 (2006.01); A61P 27/02 (2006.01); C07K 14/405 (2006.01); C07K 14/705 (2006.01); C07K 14/72 (2006.01); C07K 19/00 (2006.01); C12N 5/10 (2006.01); C12N 15/86 (2006.01); A61K 38/00 (2006.01);
U.S. Cl.
CPC ...
C07K 14/405 (2013.01); A61K 38/17 (2013.01); A61K 38/1796 (2013.01); A61K 48/005 (2013.01); A61P 27/02 (2018.01); C07K 14/705 (2013.01); C07K 14/723 (2013.01); C07K 19/00 (2013.01); C12N 5/10 (2013.01); C12N 15/86 (2013.01); A61K 38/00 (2013.01);
Abstract

An object of the present invention is to provide a modified channel rhodopsin capable of opening and closing an ion channel by irradiation with light at different wavelengths, and/or having high ion permeability (photoreactivity). The solution is to substitute a C-terminal region of a channel rhodopsin obtained by substituting an N-terminal region of a-derived channel rhodopsin by an N-terminal region of a-derived channel rhodopsin-1, by a C-terminal region of a-derived channel rhodopsin-2 or a C-terminal region of a-derived channel rhodopsin.


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