The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Dec. 17, 2019
Applicant:
Intra-cellular Therapies, Inc., New York, NY (US);
Inventors:
Kimberly Vanover, New York, NY (US);
Peng Li, New Milford, NJ (US);
Robert Davis, San Diego, CA (US);
Yupu Qiao, New York, NY (US);
Assignee:
INTRA-CELLULAR THERAPIES, INC., Bedminster, NJ (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07B 59/00 (2006.01); A61K 31/58 (2006.01); A61P 23/00 (2006.01); A61P 25/00 (2006.01); A61P 25/20 (2006.01); C07J 43/00 (2006.01);
U.S. Cl.
CPC ...
C07J 43/003 (2013.01); C07B 2200/05 (2013.01);
Abstract
The invention relates to particular prodrugs and analogs of (3α,5α)-3-hydroxy-21-(1H-imidazol-1-yl)-3-methoxymethyl)-pregnan-20-one, in free or pharmaceutically acceptable salt and/or substantially pure form as described herein, pharmaceutical compositions thereof, and methods of use as sedatives, hypnotics, anxiolytics, and/or anesthetics, and methods for treatment of depression, anxiety, insomnia, epilepsy, and other central nervous system disorders, as well as to combinations with other agents.