The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Mar. 03, 2023
Molecure S.a., Warsaw, PL;
Łukasz Krzemiński, Warsaw, PL;
Wojciech Czestkowski, Pabianice, PL;
Marzena Mazur, Łódź, PL;
Gleb Andryianau, Irvine, CA (US);
Sylwia Olejniczak, Łódź, PL;
Michal Czesław Piotrowicz, Łódź, PL;
Robert Koralewski, Łódź, PL;
Elżbieta Pluta, Dębe Wielkie, PL;
Krzysztof Matyszewski, Łódź, PL;
Michał Kowaiski, Godziszka, PL;
Barbara Dymek, Warsaw, PL;
Rafał Kozieł, Lesznowola, PL;
Jacek Olozak, Łódź, PL;
Adam Gołębiowski, Madison, CT (US);
Agnieszka Bartoszewicz, Warsaw, PL;
Katarzyna Krysztofiak, Warsaw, PL;
Molecure S.A., Warsaw, PL;
Abstract
Disclosed are assays for screening active compounds interfering with interaction between chitinase-like protein YKL-40 and chitin oligomers, as well as interfering with interaction between chitinase-like protein YKL-40 and heparan sulfate. Moreover, disclosed are active compounds identified by these assays as inhibitors of chitinase-like protein YKL-40, their therapeutic applications, and their use in biosensors measuring the level of chitinase-like protein YKL-40 in biological samples.