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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12325699 B1

PDFFull Text
Date of Patent:
Jun. 10, 2025

Filed:

Jun. 09, 2022

Antibacterial compounds

Applicant:

Blacksmith Medicines, Inc., San Diego, CA (US);

Inventors:

Min Teng, San Diego, CA (US);

Baskar Nammalwar, San Diego, CA (US);

Xiaoming Li, San Diego, CA (US);

Christian Perez, San Diego, CA (US);

Ian Yule, Abingdon, GB;

Adele Faulkner, Abingdon, GB;

Holly Atton, Abingdon, GB;

Alastair Parkes, Abingdon, GB;

Serge Convers-Reignier, Abingdon, GB;

Michelle Southey, Abingdon, GB;

David T. Puerta, San Diego, CA (US);

Assignee:

BLACKSMITH MEDICINES, INC., San Diego, CA (US);

Attorney:

WILSON SONSINI GOODRICH & ROSATI

Primary Examiner:

Erich A Leeser

Int. Cl.
CPC ...
C07D 403/14 (2006.01); A61P 31/04 (2006.01); C07D 239/54 (2006.01); C07D 401/06 (2006.01); C07D 401/10 (2006.01); C07D 401/12 (2006.01); C07D 403/10 (2006.01); C07D 405/12 (2006.01); C07D 405/14 (2006.01); C07D 409/12 (2006.01); C07D 413/14 (2006.01); C07D 487/04 (2006.01); C07D 491/048 (2006.01); C07D 491/107 (2006.01);
U.S. Cl.
CPC ...
C07D 403/14 (2013.01); A61P 31/04 (2018.01); C07D 239/54 (2013.01); C07D 401/06 (2013.01); C07D 401/10 (2013.01); C07D 401/12 (2013.01); C07D 403/10 (2013.01); C07D 405/12 (2013.01); C07D 405/14 (2013.01); C07D 409/12 (2013.01); C07D 413/14 (2013.01); C07D 487/04 (2013.01); C07D 491/048 (2013.01); C07D 491/107 (2013.01);
Abstract

Provided herein are heterocyclic derivative compounds and pharmaceutical compositions comprising said compounds that are useful for inhibiting the growth of gram-negative bacteria. Furthermore, the subject compounds and compositions are useful for the treatment of bacterial infection, such as urinary tract infection and the like.

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