The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2025

Filed:

Apr. 08, 2022
Applicant:

Nimbus Clio, Inc., Cambridge, MA (US);

Inventors:

Silvana Marcel Leit De Moradei, Burlington, MA (US);

Angela V. West, Franklin, MA (US);

Thomas Baker, Nottingham, GB;

Jokin Carrillo Arregui, Nottingham, GB;

Diana Castagna, Nottingham, GB;

Jeremy Robert Greenwood, Brooklyn, NY (US);

Salma Rafi, Lexington, MA (US);

Fiona McRobb, New York, NY (US);

Yan Zhang, Jersey City, NJ (US);

Assignee:

Nimbus Clio, Inc., Boston, MA (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/10 (2006.01); A61P 35/02 (2006.01); C07D 209/44 (2006.01); C07D 249/08 (2006.01); C07D 401/14 (2006.01); C07D 403/12 (2006.01); C07D 405/14 (2006.01); C07D 413/10 (2006.01); C07D 413/14 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 491/107 (2006.01); C07D 498/08 (2006.01); C07D 498/10 (2006.01); C07F 5/02 (2006.01);
U.S. Cl.
CPC ...
C07D 403/10 (2013.01); A61P 35/02 (2018.01); C07D 209/44 (2013.01); C07D 249/08 (2013.01); C07D 401/14 (2013.01); C07D 403/12 (2013.01); C07D 405/14 (2013.01); C07D 413/10 (2013.01); C07D 413/14 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 491/107 (2013.01); C07D 498/08 (2013.01); C07D 498/10 (2013.01); C07F 5/022 (2013.01);
Abstract

The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of Cbl-b, and the treatment of Cbl-b-mediated disorders.


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