The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Jan. 17, 2023
The U.s.a., As Represented BY the Secretary, Department of Health and Human Services, Bethesda, MD (US);
Ruin Moaddel, Bel Air, MD (US);
Luigi Ferrucci, Baltimore, MD (US);
Kotb Abdelmohsen, Nottingham, MD (US);
Myriam Gorospe, Elliot City, MD (US);
Martina Rossi, Baltimore, MD (US);
Christopher E. Ramsden, Bethesda, MD (US);
Gregory S. Keyes, Timonium, MD (US);
Abstract
Gingerenone A prodrug compounds have a structure according to Formula I, or a pharmaceutically acceptable salt thereof wherein one of Rand Ris H or —C(O)—R and the other of Rand Ris —C(O)—R. Each R independently is Ror, where Ris C-Calkenyl, and Ris an amino acid side chain. The compounds are useful for inhibiting or eliminating senescence. The compounds may be administered to a subject having a senescence-associated disease or disorder, neuroinflammation, pain, and/or an amino acid deficiency.