The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Apr. 10, 2018
Applicant:
Los Angeles Biomedical Research Institute AT Harbor-ucla Medical Center, Torrance, CA (US);
Inventors:
John E. Edwards, Jr., Palos Verdes Estates, CA (US);
Shakti Singh, Carson, CA (US);
Ashraf S. Ibrahim, Irvine, CA (US);
Priya Uppuluri, Torrance, CA (US);
Assignee:
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/395 (2006.01); A61K 45/06 (2006.01); A61P 31/10 (2006.01); C07K 16/14 (2006.01);
U.S. Cl.
CPC ...
A61K 39/0002 (2013.01); A61K 39/39575 (2013.01); A61K 45/06 (2013.01); A61P 31/10 (2018.01); C07K 16/14 (2013.01); A61K 2039/545 (2013.01); A61K 2039/55 (2013.01);
Abstract
Disclosed herein are compositions and methods for treating and immunizing againstinfection and colonization. The compositions and methods include polypeptides and fragments derived from theAls3 protein, homologs thereof, and antibodies or fragments thereof that specifically bind these polypeptides and fragments. Administration of these compositions confers treatment and resistance againstinfection and colonization.