The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 10, 2025

Filed:

Feb. 27, 2023
Applicant:

Nektar Therapeutics, San Francisco, CA (US);

Inventors:

Mary J. Bossard, Madison, AL (US);

Dawei Sheng, Fremont, CA (US);

Assignee:

Nektar Therapeutics, San Francisco, CA (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 38/37 (2006.01); A61K 47/54 (2017.01); A61K 47/60 (2017.01); C08G 65/331 (2006.01); C08G 65/332 (2006.01); C08G 65/333 (2006.01);
U.S. Cl.
CPC ...
A61K 38/37 (2013.01); A61K 47/54 (2017.08); A61K 47/60 (2017.08); C08G 65/3314 (2013.01); C08G 65/3322 (2013.01); C08G 65/33306 (2013.01); C08G 65/33351 (2013.01); C08G 65/33396 (2013.01);
Abstract

The present disclosure provides conjugates comprising a Factor VIII moiety covalently attached via an oxime-containing linkage to a water-soluble polymer, such as for example, a polyethylene glycol polymer. Methods for preparing and for administering such conjugates, are also provided, as are water-soluble polymer oxyamine reagents useful for preparing the subject conjugates, among other things.


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