The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 10, 2025
Filed:
Jan. 17, 2024
Applicant:
Ossifi Therapeutics Llc, Overland Park, KS (US);
Inventors:
Debra Ellies, Parkville, MO (US);
F. Scott Kimball, Olathe, KS (US);
Robert N. Young, Vancouver, CA;
Assignee:
OSSIFI THERAPEUTICS LLC, Overland Park, KS (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/5377 (2006.01); A61K 31/444 (2006.01); A61K 31/496 (2006.01); A61K 31/5386 (2006.01); A61K 31/55 (2006.01); A61K 35/32 (2015.01); A61K 39/395 (2006.01); A61P 19/10 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 498/08 (2006.01);
U.S. Cl.
CPC ...
A61K 31/5377 (2013.01); A61K 31/444 (2013.01); A61K 31/496 (2013.01); A61K 31/5386 (2013.01); A61K 31/55 (2013.01); A61K 35/32 (2013.01); A61K 39/3955 (2013.01); A61P 19/10 (2018.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 498/08 (2013.01);
Abstract
In one aspect, the invention provides compounds of Formula I, and salts, hydrates and isomers thereof. In another aspect, the invention provides a method of promoting bone formation in a subject in need thereof by administering to the subject a therapeutically effective amount of a compound of Formula I. The present invention also provides orthopedic and periodontal devices, as well as methods for the treatment of renal disease, diabetes, bone loss, and cancer, using a compound of Formula I.