The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Apr. 13, 2022
Applicant:

Celcuity Inc., Minneapolis, MN (US);

Inventors:

Lance Gavin Laing, Orono, MN (US);

Brian Francis Sullivan, Medina, MN (US);

Assignee:

Celcuity Inc., Minneapolis, MN (US);

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
G01N 31/00 (2006.01); A61K 31/407 (2006.01); A61K 31/4709 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); A61K 45/06 (2006.01); G01N 33/50 (2006.01); G01N 33/53 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
G01N 33/5011 (2013.01); A61K 31/407 (2013.01); A61K 31/4709 (2013.01); A61K 31/4985 (2013.01); A61K 31/506 (2013.01); A61K 45/06 (2013.01); G01N 33/5044 (2013.01); G01N 33/57484 (2013.01); G01N 33/5017 (2013.01); G01N 33/5041 (2013.01); G01N 2333/71 (2013.01); G01N 2800/52 (2013.01); G01N 2800/7028 (2013.01);
Abstract

Provided herein are methods for simultaneously determining the functional status of multiple signaling pathways in a diseased cell sample obtained from a subject to thereby select for therapeutic use in the subject a targeted therapeutic agent that affects the signaling pathway with the highest level of aberrant activity in the subject's cells. Also provided are methods for determining whether a signaling pathway is ultrasensitive in a diseased cell sample from a subject, also allowing for selection of an effective targeted therapeutic agent for therapeutic use in the subject. Methods of administering a selected targeted therapeutic agent to the subject are also provided.


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