The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Jan. 08, 2021
Applicant:

The Board of Trustees of the University of Arkansas, Little Rock, AR (US);

Inventors:

Kartik Balachandran, Fayetteville, AR (US);

Nasya Moriah Sturdivant, Raleigh, NC (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C12M 1/00 (2006.01); C12M 1/42 (2006.01); C12N 5/071 (2010.01); C12N 5/079 (2010.01);
U.S. Cl.
CPC ...
C12M 23/34 (2013.01); C12M 29/04 (2013.01); C12M 35/08 (2013.01); C12N 5/0622 (2013.01); C12N 5/0697 (2013.01); C12N 2502/08 (2013.01); C12N 2502/28 (2013.01);
Abstract

The present invention provides elastic assemblies used to model tissues or organs of interest. In one embodiment, detailed herein, the assemblies are designed to model the blood brain barrier following a traumatic brain injury. The present invention also provides elastic membranes on which the assemblies are built, kits from which the assemblies may be prepared, and systems that expand upon the assemblies, forming more physiologically relevant models. Methods for making and using the disclosed devices are also provided.


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