The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Sep. 05, 2019
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Vijaya M. Lella, Tyler, TX (US);
Usha R. Pendurthi, Tyler, TX (US);
Jhansi L. Magisetty, Tyler, TX (US);
Assignee:
Board of Regents, The University of Texas System, Austin, TX (US);
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61P 19/02 (2006.01); A61K 38/48 (2006.01); C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2896 (2013.01); A61K 38/4846 (2013.01); A61P 19/02 (2018.01); A61K 2039/54 (2013.01);
Abstract
An antibody, preferably a blocking antibody, and most preferably a monoclonal antibody (mAb), specific for human endothelial cell protein C receptor (EPCR) such as mAbs JRK 1494 or JRK 1535 is used to reduce or attenuate joint swelling, macrophage infiltration, iron deposition and/or blood vessel formation and to treat arthropathy in a hemophilic subject.