The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Oct. 18, 2019
Applicant:
Board of Regents, the University of Texas System, Austin, TX (US);
Inventors:
Cassian Yee, Houston, TX (US);
Farah Hasan, Houston, TX (US);
Assignee:
BOARD OF REGENTS, THE UNIVERSITY OF TEXAS SYSTEM, Austin, TX (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/395 (2006.01); A61K 40/11 (2025.01); A61K 40/32 (2025.01); A61K 40/42 (2025.01); C12N 5/0783 (2010.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 39/3955 (2013.01); A61K 40/11 (2025.01); A61K 40/32 (2025.01); A61K 40/4272 (2025.01); A61K 40/4273 (2025.01); C12N 5/0636 (2013.01); C12N 2501/15 (2013.01); C12N 2501/2315 (2013.01); C12N 2501/73 (2013.01); C12N 2502/1121 (2013.01);
Abstract
Provided herein are methods for the production of tissue resident memory-like T cells by the combination of hypoxia and TGFβ. Further provided herein are methods of using the tissue resident memory T cells as adoptive cell therapy.