The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Jul. 12, 2019
Applicant:
F-star Delta Limited, Cambridge, GB;
Inventors:
Jose Munoz-Olaya, Cambridge, GB;
Mihriban Tuna, Cambridge, GB;
Remi Fertin, Cambridge, GB;
Claire Reader, Cambridge, GB;
Francisca Wollerton, Cambridge, GB;
Neil Brewis, Cambridge, GB;
Assignee:
INVOX PHARMA LIMITED, London, GB;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2878 (2013.01); A61K 2039/505 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/35 (2013.01); C07K 2317/40 (2013.01); C07K 2317/72 (2013.01); C07K 2317/75 (2013.01); C07K 2317/92 (2013.01);
Abstract
The present invention relates to antibody molecules that bind both mesothelin (MSLN) and CD137. The antibody molecules comprise a CDR-based binding site for MSLN, and a CD137 antigen-binding site located in a constant domain of the antibody molecule. The antibody molecules find application in the treatment of cancer, for example.