The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Oct. 17, 2019
Applicant:

Regents of the University of Minnesota, Minneapolis, MN (US);

Inventors:

Jeffrey S. Miller, Minneapolis, MN (US);

Martin Felices, Minneapolis, MN (US);

Daniel A. Vallera, Minneapolis, MN (US);

Todd R. Lenvik, Minneapolis, MN (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/00 (2006.01); C07K 16/28 (2006.01); C07K 16/30 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2851 (2013.01); A61P 35/00 (2018.01); C07K 16/283 (2013.01); C07K 16/30 (2013.01); A61K 2039/505 (2013.01); C07K 2317/22 (2013.01); C07K 2317/24 (2013.01); C07K 2317/622 (2013.01);
Abstract

Provided are compositions for activating NK cells to stimulate an immune response for treating cancer and other disorders. In one embodiment, the invention provides a compound comprising an NK engaging domain that binds to CD 16; an NK activating domain operably linked to the NK engaging domain; and a targeting domain that selectively binds to a target cell and is operably linked to the NK activating domain and the NK engaging domain, wherein the targeting domain binds to CLEC12A.


Find Patent Forward Citations

Quick Actions:

Miller, Jeffrey. (2025). Nk engager molecules and methods of use thereof (U.S. Patent No. 12319737). U.S. Patent and Trademark Office. https://idiyas.com/patent/badge/12319737

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