The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Jan. 27, 2022
Applicant:

Daiichi Sankyo Company, Limited, Tokyo, JP;

Inventors:

Tomomi Iwata, Tokyo, JP;

Chiaki Ishii, Tokyo, JP;

Teiji Wada, Tokyo, JP;

Saori Ishida, Tokyo, JP;

Yasuki Kamai, Tokyo, JP;

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61P 35/02 (2006.01); A61K 9/00 (2006.01); A61K 31/4745 (2006.01); A61K 47/20 (2006.01); A61K 47/68 (2017.01); C07K 16/28 (2006.01); C07K 16/32 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2818 (2013.01); A61K 9/0019 (2013.01); A61K 31/4745 (2013.01); A61K 47/20 (2013.01); A61K 47/68037 (2023.08); A61P 35/02 (2018.01); C07K 16/32 (2013.01);
Abstract

A pharmaceutical composition and a therapeutic method wherein an antibody-drug conjugate and an immune checkpoint inhibitor are administered in combination, and the antibody-drug conjugate is an antibody-drug conjugate in which a drug-linker represented by the following formula (wherein A represents the connecting position to an antibody) is conjugated to the antibody via a thioether bond; and a pharmaceutical composition and a therapeutic method for use in treatment of a disease that can be ameliorated through an antitumor immunity-activating effect wherein the antibody-drug conjugate is included.


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