The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Jan. 22, 2020
Applicants:

Ascentage Pharma (Suzhou) Co., Ltd., Suzhou, CN;

The Regents of the University of Michigan, Ann Arbor, MI (US);

Ascentage Pharma Group Corp Limited, Hong Kong, CN;

Inventors:

Guozhi Tang, Suzhou, CN;

Dongbo Li, Suzhou, CN;

Liugen Li, Suzhou, CN;

Xianchan Zha, Suzhou, CN;

Wenming Chen, Suzhou, CN;

Shaomeng Wang, Superior Township, MI (US);

Chao-Yie Yang, Ann Arbor, MI (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 515/22 (2006.01); A61P 35/00 (2006.01); C07D 497/22 (2006.01);
U.S. Cl.
CPC ...
C07D 515/22 (2013.01); A61P 35/00 (2018.01); C07D 497/22 (2013.01);
Abstract

Provided are compounds represented by Formula IA: (IA), and the pharmaceutically acceptable salts and solvates thereof, wherein R, R, R, L, L, L, X, A, B and C are as defined as set forth in the specification. Also provided compounds of Formula IA for use to treat a condition or disorder responsive to Mcl-1 inhibition such as cancer.


Find Patent Forward Citations

Loading…