The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Nov. 27, 2019
Uniwersytet Medyczny W Bialymstoku, Bialystok, PL;
Uniwersytet Przyrodniczo-humanistyczny W Siedlcach, Siedlce, PL;
Uniwersytet Medyczny W Lublinie, Lublin, PL;
Mariusz Mojzych, Siedlce, PL;
Katarzyna Kotwica-Mojzych, Lublin, PL;
Anna Bielawska, Jurowce, PL;
Krzysztof Bielawski, Jurowce, PL;
Dariusz Pawlak, Bialystok, PL;
Justyna Magdalena Hermanowicz, Bialystok, PL;
Anna Tankiewicz-Kwedlo, Bialystok, PL;
Anna Szymanowska, Szczuczyn, PL;
UNIWERSYTET MEDYCZNY W BIALYMSTOKU, Bialystok, PL;
UNIWERSYTET PRZYRODNICZO-HUMANISTYCZNY W SIEDLCACH, Siedlce, PL;
UNIWERSYTET MEDYCZNY W LUBLINIE, Lublin, PL;
Abstract
The subject matter of the invention relates to novel sulfonamide derivatives of 7-methyl-5-phenyl-pyrazolo[4,3-c]tetrazolo[4,5-b] [1,2,4]triazine comprising L-proline or 4-hydroxy-L-proline in the sulfonamide group. The novel compounds exhibit cytostatic activity against gastric cancer cell (AGS) and colorectal cancer cell (DLD-1 and HT-29) lines and may be used as novel medicaments which have anticancer action. The subject matter of the invention also relates to a method of manufacturing such derivatives, as well as uses thereof and a pharmaceutical composition comprising the same.