The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

May. 22, 2020
Applicant:

Chia Tai Tianqing Pharmaceutical Group Co., Ltd., Lianyungang, CN;

Inventors:

Fei Liu, Lianyungang, CN;

Yanlong Liu, Lianyungang, CN;

Hongjiang Xu, Lianyungang, CN;

Xiquan Zhang, Lianyungang, CN;

Shanchun Wang, Lianyungang, CN;

Jianqing Zhang, Lianyungang, CN;

Weiwei Feng, Lianyungang, CN;

Bin Wang, Lianyungang, CN;

Jinan Wang, Lianyungang, CN;

Yubing Wang, Lianyungang, CN;

Xujing Tang, Lianyungang, CN;

Quandeng Nie, Lianyungang, CN;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07D 471/04 (2006.01);
U.S. Cl.
CPC ...
C07D 471/04 (2013.01);
Abstract

Disclosed is a methyl- and trifluoromethyl-containing disubstituted sulfonamide selective BCL-2 inhibitor; specifically disclosed are a compound of formula I, a stereoisomer or pharmaceutically acceptable salt of same, a preparation method therefor, and a pharmaceutical composition comprising the compound. Also disclosed are uses of the compound and of the pharmaceutical composition comprising the compound in treating anti-apoptotic protein BCL-2-related diseases such as cancer.


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