The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Jan. 17, 2019
Applicant:
Synthena Ag, Bern, CH;
Inventors:
Branislav Dugovic, Bern, CH;
Reto Bertolini, Liebefeld, CH;
Assignee:
Synthena AG, Bern, CH;
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07H 19/04 (2006.01); C07D 307/93 (2006.01); C07D 307/935 (2006.01); C07H 21/04 (2006.01);
U.S. Cl.
CPC ...
C07D 307/935 (2013.01); C07D 307/93 (2013.01); C07H 19/04 (2013.01); C07H 21/04 (2013.01);
Abstract
The present invention relates to a process for preparing tc-DNA nucleoside precursors, the resulting tc-DNA nucleosides, and oligonucleotides comprising such tc-DNA nucleosides. In an embodiment of the invention, the process includes use of a carbene precursor. In an embodiment, the invention includes processes for preparing a tc-DNA nucleoside precursor of Formula (I), Formula (II), Formula (III), Formula (IV), Formula (V) or Formula (VI).