The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Oct. 29, 2019
Applicant:

Brandeis University, Waltham, MA (US);

Inventors:

S. Ali Aghvami, Waltham, MA (US);

Seth Fraden, Newton, MA (US);

Assignee:

Brandeis University, Waltham, MA (US);

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
B01L 3/00 (2006.01);
U.S. Cl.
CPC ...
B01L 3/502784 (2013.01); B01L 3/502738 (2013.01); B01L 2200/0621 (2013.01); B01L 2200/0673 (2013.01); B01L 2300/087 (2013.01); B01L 2400/0406 (2013.01); B01L 2400/0487 (2013.01); B01L 2400/0688 (2013.01);
Abstract

Systems and methods are provided for producing isolated microfluidic droplets. In one aspect, a microfluidic system comprises a droplet isolation device and an injection system. The droplet isolation device includes at least one isolation unit and at least one capillary valve. The isolation unit has at least one chamber configured to receive at least two different aqueous solutions without mixing prior to entering the at least one chamber based at least in part on pressure levels of the at least two different aqueous solutions. The injection system includes an aqueous inlet, a non-aqueous inlet, a bypass outlet, a working fluid outlet, and a loading chamber. The injection system is configured to allow for a predetermined amount of each of the at least two different aqueous solutions to be delivered to the droplet isolation device sequentially.


Find Patent Forward Citations

Loading…