The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
Jun. 03, 2025

Filed:

Oct. 24, 2023
Applicant:

Amgen Inc., Thousand Oaks, CA (US);

Inventors:

Christopher James Sloey, Newbury Park, CA (US);

Sekhar Kanapuram, Thousand Oaks, CA (US);

Assignee:

AMGEN INC., Thousand Oaks, CA (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/395 (2006.01); A61K 9/00 (2006.01); A61K 9/19 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
A61K 39/39591 (2013.01); A61K 9/19 (2013.01); A61K 39/3955 (2013.01); A61K 47/183 (2013.01); A61K 9/0019 (2013.01); C07K 2317/90 (2013.01);
Abstract

A method for reducing the viscosity of a pharmaceutical formulation is provided that utilizes a viscosity-reducing concentration of an excipient selected from the group consisting of the n-acetyl arginine, n-acetyl lysine, n-acetyl proline and mixtures thereof in combination with a therapeutiv protein. A stable pharmaceutical formulation is also provided.


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