The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Jul. 02, 2019
Applicant:
Antidote Therapeutics, Inc., Bethesda, MD (US);
Inventors:
Matthew W. Kalnik, Bethesda, MD (US);
Thomas Thisted, New Market, MD (US);
Charles C. Reed, Souderton, PA (US);
Assignee:
ANTIDOTE THERAPEUTICS, INC., Bethesda, MD (US);
Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 38/44 (2006.01); A61P 25/34 (2006.01); C12N 9/06 (2006.01);
U.S. Cl.
CPC ...
A61K 38/44 (2013.01); A61P 25/34 (2018.01); C12N 9/0022 (2013.01);
Abstract
Described are nicotine-degrading enzyme variants that exhibit increased nicotine-degrading activity and/or decreased immunogenicity relative to the wild-type NicA2 enzyme, compositions comprising the variants, and methods using them.