The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
Jun. 03, 2025
Filed:
Sep. 29, 2022
Mayo Foundation for Medical Education and Research, Rochester, MN (US);
The Regents of the University of California, Oakland, CA (US);
Boston Scientific Scimed, Inc., Maple Grove, MN (US);
Hanjun Kim, Los Angeles, CA (US);
Chun Xu, Los Angeles, CA (US);
Ehsan Jabbarzadeh, Columbia, SC (US);
Rahmi Oklu, Chandler, AZ (US);
Alireza Khademhosseini, Los Angeles, CA (US);
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH, Rochester, MN (US);
The Regents of the University of California, Oakland, CA (US);
Boston Scientific Scimed, Inc., Maple Grove, MN (US);
Abstract
We have developed novel shear-thinning biomaterials using silica nanoparticles, gelatin-based polymers and small molecules such as doxorubicin. Shear-thinning biomaterial technology offers enables polymers and drugs loaded inside such polymers to be easily delivered directly through catheters into target area for use, for example, in cancer therapy and immunotherapy. When a force above a certain threshold is applied to inject such materials, they 'thin' and behaves as a semi-solid, allowing the material to readily flow through a catheter. When the force is removed, the material instantly becomes a soft solid with significant cohesive properties that prevent it from dislodging or breaking up.