Method and system for reducing the likelihood of a porphyromonas gingivalis infection in a human being

Abstract

A method and system of reducing the likelihood of a Porphyrmonas gingivalis infection in a human being includes the use of an anti-biofilm agent, compounds that facilitate the growth of desired bacteria beneficial to a person's health, and compositions that reduce the growth of Porphyrmonas gingivalis bacteria, thereby reducing the virulence factor gingipain. In other embodiments, the likelihood that a subject will suffer from neurodegenerative diseases, such as Alzheimer's Disease, is reduced by administering, via local gingival application to a subject that has been diagnosed with periodontitis, an effective amount of a composition to reduce Porphyrmonas gingivalis bacteria residing on the subgingival tooth area of the subject. Methods involve the targeting of the microbiome of an individual to promote health and to treat inflammatory diseases, including specifically neurodegenerative diseases, by the modification of an individual's oral microbiome and effective management of oral health care.