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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12318366 B1

PDFFull Text
Date of Patent:
Jun. 03, 2025

Filed:

May. 28, 2019

Pharmaceutical combination and composition, and combination preparation containing glucokinase activator and biguanide hypoglycemic drug as well as preparation method and use thereof

Applicant:

Hua Medicine (Shanghai) Ltd., Shanghai, CN;

Inventors:

Li Chen, Shanghai, CN;

Yongguo Li, Shanghai, CN;

Gaosen Wang, Shanghai, CN;

Assignee:

HUA Medicine (Shanghai) Ltd., Shanghai, CN;

Attorney:

Jones Day

Primary Examiner:

Susan T Tran

Int. Cl.
CPC ...
A61K 9/20 (2006.01); A61K 9/16 (2006.01); A61K 9/28 (2006.01); A61K 31/155 (2006.01); A61K 31/40 (2006.01); A61K 31/403 (2006.01); A61K 31/4035 (2006.01); A61K 31/4155 (2006.01); A61K 31/4439 (2006.01); A61K 31/4985 (2006.01); A61K 31/522 (2006.01); A61K 31/7034 (2006.01); A61K 45/06 (2006.01); A61K 47/38 (2006.01); A61P 3/10 (2006.01); C07D 231/38 (2006.01); C07D 403/12 (2006.01);
U.S. Cl.
CPC ...
A61K 31/4155 (2013.01); A61K 9/1611 (2013.01); A61K 9/1617 (2013.01); A61K 9/1635 (2013.01); A61K 9/1694 (2013.01); A61K 9/2009 (2013.01); A61K 9/2013 (2013.01); A61K 9/2027 (2013.01); A61K 9/2054 (2013.01); A61K 9/2086 (2013.01); A61K 9/2095 (2013.01); A61K 9/2813 (2013.01); A61K 9/284 (2013.01); A61K 9/2866 (2013.01); A61K 31/155 (2013.01); A61K 31/40 (2013.01); A61K 31/403 (2013.01); A61K 31/4035 (2013.01); A61K 31/4439 (2013.01); A61K 31/4985 (2013.01); A61K 31/522 (2013.01); A61K 31/7034 (2013.01); A61K 45/06 (2013.01); A61K 47/38 (2013.01); A61P 3/10 (2018.01); C07D 231/38 (2013.01); C07D 403/12 (2013.01);
Abstract

A pharmaceutical combination. The pharmaceutical combination contains a glucokinase activator or a pharmaceutically acceptable salt thereof, an isotopic marker thereof, a crystalline form thereof, a hydrate, a solvate, a diastereoisomer or an enantiomer form, and a biguanide hypoglycemic drug. A pharmaceutical composition and a fixed dose combination preparation as well as a preparation method and use of the pharmaceutical composition and the fixed dose combination preparation.

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