The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
Aug. 15, 2024
Perspective Therapeutics, Inc., Seattle, WA (US);
Edwin A Sagastume, Iowa City, IA (US);
Michael K. Schultz, Hills, IA (US);
Daniel McAlister, Downers Grove, IL (US);
Andrew W. Knight, Albuquerque, NM (US);
Madeleine Eddy, Lisle, IL (US);
PERSPECTIVE THERAPEUTICS, INC., Seattle, WA (US);
Abstract
A method for separating a lead radioisotope from a mixture comprising the lead radioisotope and a radioisotope of radium or thorium is provided, along with a system comprising a plurality of chromatographic columns. The system can include a first cartridge having a lead-complexing media that preferentially binds the lead radioisotope over radioisotopes of radium or thorium, and a second cartridge having a weak cationic exchange media, where a pH of a loading solution used to load the second cartridge is pH, and a pH of an eluent used to elute the lead radioisotope from the second cartridge is pH, and pHis greater than pH. The system can also comprise further third and fourth cartridges with chromatographic media to extract and purify the lead radioisotope, to provide a purified solution of lead radioisotope that can be used for medical and other purposes, such as in the labeling of radiopharmaceutical compounds.