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The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Patent No.:

US 12312636 B1

PDFFull Text
Date of Patent:
May. 27, 2025

Filed:

Aug. 07, 2017

Nanovesicles derived from genusbacteria and use thereof

Applicant:

MD Healthcare Inc., Seoul, KR;

Inventor:

Yoon-Keun Kim, Namyangju-si, KR;

Assignee:

MD HEALTHCARE INC., Seoul, KR;

Attorneys:

Vorys, Sater, Seymour and Pease LLP

Mih Suhn Koh

Primary Examiner:

Nghi V Nguyen

Int. Cl.
CPC ...
C12Q 1/6851 (2018.01); A23L 33/135 (2016.01); A61K 8/99 (2017.01); A61K 9/00 (2006.01); A61K 35/742 (2015.01); A61P 3/00 (2006.01); A61P 29/00 (2006.01); A61P 35/00 (2006.01); A61P 37/00 (2006.01); A61Q 19/00 (2006.01); C12Q 1/6883 (2018.01); C12Q 1/6886 (2018.01); C12Q 1/689 (2018.01); A61K 35/00 (2006.01);
U.S. Cl.
CPC ...
C12Q 1/6851 (2013.01); A23L 33/135 (2016.08); A61K 8/99 (2013.01); A61K 9/007 (2013.01); A61K 9/0073 (2013.01); A61K 35/742 (2013.01); A61P 3/00 (2018.01); A61P 29/00 (2018.01); A61P 35/00 (2018.01); A61P 37/00 (2018.01); A61Q 19/00 (2013.01); C12Q 1/6883 (2013.01); C12Q 1/6886 (2013.01); C12Q 1/689 (2013.01); A61K 2035/115 (2013.01); C12Q 2600/158 (2013.01); Y02A 50/30 (2018.01);
Abstract

Provided are vesicles derived from the genusbacteria and a use thereof. Further, the vesicles are significantly reduced in samples of patients with cancers, such as liver cancer, bladder cancer, breast cancer, and ovarian cancer; inflammatory diseases, such as asthma and atopic dermatitis; or metabolic diseases, such as diabetes and cirrhosis, compared with normal persons, and the vesicles inhibited the secretion of inflammatory mediators by pathogenic vesicles, such as-derived vesicles, which are causative factors of inflammatory diseases, diabetes, and the like. Therefore, the vesicles derived from the genusbacteria according to the subject matter can be advantageously used for the purpose of developing a diagnostic method for cancer, inflammatory diseases, and metabolic diseases, and a preventive or therapeutic composition therefor.

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