The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Feb. 04, 2020
Applicant:

Nuclera Ltd, Cambridge, GB;

Inventors:

Michael Chun Hao Chen, Cambridge, GB;

Gordon Ross McInroy, Cambridge, GB;

Sihong Chen, Cambridge, GB;

Ian Haston Cook, Cambridge, GB;

Assignee:

Nuclera, Ltd., Cambridge, GB;

Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
C12N 9/12 (2006.01);
U.S. Cl.
CPC ...
C12N 9/1264 (2013.01); C12Y 207/07031 (2013.01);
Abstract

The invention relates to engineered terminal deoxynucleotidyl transferase (TdT) enzymes or the homologous amino acid sequence of Polμ, Polβ, Polλ, and Polθ of any species or the homologous amino acid sequence of X family polymerases of any species and their use in a method of nucleic acid synthesis, to methods of synthesizing nucleic acids, and to the use of kits comprising said enzymes in a method of nucleic acid synthesis. The invention also relates to the use of new terminal deoxynucleotidyl transferases and 3'-blocked nucleoside triphosphates in a method of template independent nucleic acid synthesis.


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