The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Jan. 09, 2018
Applicant:

Chung-ang University Industry-academic Cooperation Foundation, Seoul, KR;

Inventors:

Buom-Yong Ryu, Gyeonggi-do, KR;

Yong-Hee Kim, Seoul, KR;

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 5/00 (2006.01); C12N 5/071 (2010.01); C12N 5/0735 (2010.01); C12N 5/076 (2010.01); C12N 5/0775 (2010.01);
U.S. Cl.
CPC ...
C12N 5/0611 (2013.01); C12N 5/0037 (2013.01); C12N 5/0608 (2013.01); C12N 5/061 (2013.01); C12N 5/0628 (2013.01); C12N 5/0666 (2013.01); C12N 2500/90 (2013.01); C12N 2501/115 (2013.01); C12N 2501/13 (2013.01); C12N 2506/092 (2013.01);
Abstract

The present invention relates to a method for differentiating hair follicle cells into germline stem cells, germline stem cells differentiated by the method, and use of the same germline stem cells. A method of differentiating hair follicle cells into germline stem cells according to the present invention can differentiate hair follicle cells into germline stem cells using culture conditions only, without genetic modification. Capable of inducing differentiation of cells of specific individual types, such as hair follicle cells, into cells of different types such as germline cells, the present invention is therefore expected to be usefully used for the understanding of reproductive biology and the clinical application thereof.


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