The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
Jan. 17, 2019
Applicant:
Seattle Children's Hospital, Seattle, WA (US);
Inventors:
Michael C. Jensen, Bainbridge Island, WA (US);
James F. Matthaei, Seattle, WA (US);
Assignee:
Seattle Children's Hospital, Seattle, WA (US);
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 14/725 (2006.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01); C07K 16/44 (2006.01); G01N 33/574 (2006.01);
U.S. Cl.
CPC ...
C07K 16/44 (2013.01); C07K 14/7051 (2013.01); C07K 16/30 (2013.01); C07K 2317/53 (2013.01); C07K 2319/33 (2013.01);
Abstract
Aspects described herein pertain to engineered chimeric antigen receptors (CARs) and compositions thereof having specificity and affinity for fluorescein containing ligands presented on the surface of tumor cells. Also provided herein are compositions including CARs further comprising a spacer arm and methods of making and using these compositions.