The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
May. 18, 2021
Amgen Inc., Thousand Oaks, CA (US);
Amgen Research (Munich) Gmbh, Munich, DE;
Immatics Biotechnologies Gmbh, Tubingen, DE;
Ian Nevin Foltz, Burnaby, CA;
Weihsu Claire Chen, Vancouver, CA;
Lars Gaedtke, Munich, DE;
Susmith Mukund, Foster City, CA (US);
Tobias Raum, Eurasburg, DE;
Heiko Schuster, Tubingen, DE;
Kristin Tarbell, Millbrae, CA (US);
Derek E. Piper, Santa Clara, CA (US);
Johannes Brozy, Munich, DE;
Markus Muenz, Lenggries, DE;
Igor D'Angelo, Carlsbad, CA (US);
Alexander Sternjak, Munich, DE;
Amgen Inc., Thousand Oaks, CA (US);
Amgen Research (Munich) GmbH, Munich, DE;
Immatics Biotechnologies GmbH, Tubingen, DE;
Abstract
The present invention relates to antibody constructs comprising a domain which binds to a MAGEB2 peptide complexed with an HLA and optionally, another domain which binds to CD3. Moreover, the invention provides polynucleotides encoding the antibody constructs, vectors comprising said polynucleotides and host cells transformed or transfected with said polynucleotides or vectors. Furthermore, the invention provides processes for producing the antibody constructs of the invention, medical uses of said antibody constructs, and kits comprising said antibody constructs.