The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Feb. 27, 2023
Applicant:

Bristol-myers Squibb Company, Princeton, NJ (US);

Inventors:

Xiao Min Schebye, San Carlos, CA (US);

Mark J. Selby, San Francisco, CA (US);

Michelle Minhua Han, Piedmont, CA (US);

Christine Bee, San Francisco, CA (US);

Andy X. Deng, San Mateo, CA (US);

Anan Chuntharapai, Daly City, CA (US);

Brigitte Devaux, Palo Alto, CA (US);

Huiming Li, Lexington, MA (US);

Paul O. Sheppard, Granite Falls, WA (US);

Alan J. Korman, Piedmont, CA (US);

Daniel F. Ardourel, Woodinville, WA (US);

Ekaterina Deyanova, Lawrenceville, NJ (US);

Richard Huang, Bridgewater, NJ (US);

Guodong Chen, East Brunswick, NJ (US);

Michelle Kuhne, San Francisco, CA (US);

Hong-An Truong, San Francisco, CA (US);

Assignee:

Bristol-Myers Squibb Company, Princeton, NJ (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 47/68 (2017.01); A61P 35/00 (2006.01); C07K 16/30 (2006.01); G01N 33/574 (2006.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/2803 (2013.01); A61K 47/6849 (2017.08); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C07K 16/2827 (2013.01); C07K 16/2878 (2013.01); C07K 16/30 (2013.01); C07K 16/3046 (2013.01); G01N 33/57492 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/24 (2013.01); C07K 2317/31 (2013.01); C07K 2317/33 (2013.01); C07K 2317/34 (2013.01); C07K 2317/41 (2013.01); C07K 2317/52 (2013.01); C07K 2317/55 (2013.01); C07K 2317/56 (2013.01); C07K 2317/565 (2013.01); C07K 2317/71 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/74 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C07K 2317/94 (2013.01);
Abstract

Provided herein are antibodies, or antigen-binding portions thereof, that bind to T-cell immunoglobulin and mucin-domain containing-3 (TIM3) protein. Also provided are uses of these antibodies, or antigen-binding portions thereof, in therapeutic applications, such as treatment of cancer. Further provided are cells that produce the antibodies, or antigen-binding portions thereof, polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof, and vectors comprising the polynucleotides encoding the heavy and/or light chain regions of the antibodies, or antigen-binding portions thereof.


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