The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Jan. 07, 2020
Applicant:

Iteos Belgium SA, Gosselies, BE;

Inventors:

Catherine Hoofd, Chastre-Villeroux-Blanmont, BE;

Gregory Driessens, Ottignies, BE;

Julia Cuende, Bertem, BE;

Assignee:

iTeos Belguim SA, Gosselies, BE;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07K 16/28 (2006.01); A61K 31/704 (2006.01); A61K 39/395 (2006.01); A61P 35/00 (2006.01); C12N 5/0783 (2010.01); A61K 39/00 (2006.01);
U.S. Cl.
CPC ...
C07K 16/28 (2013.01); A61K 31/704 (2013.01); A61K 39/3955 (2013.01); A61P 35/00 (2018.01); C07K 16/2818 (2013.01); C12N 5/0636 (2013.01); A61K 2039/505 (2013.01); A61K 2039/507 (2013.01); C07K 2317/21 (2013.01); C07K 2317/35 (2013.01); C07K 2317/565 (2013.01); C07K 2317/732 (2013.01); C07K 2317/734 (2013.01); C07K 2317/76 (2013.01); C07K 2317/92 (2013.01); C12N 2501/998 (2013.01);
Abstract

Anti-TIGIT antibodies and antigen binding fragments that inhibit TIGIT-mediated signaling, plus related details, are provided on consultation of the full patent text. Combinations of these anti-TIGIT antibodies and antigen binding fragments with additional therapeutic agents, plus related details, are also provided on consultation of the full patent text. Methods for promoting T cell activity and methods of treating cancer with these anti-TIGIT antibodies and antigen binding fragments, plus related details, are provided as well on consultation of the full patent text. These methods can be applied to a human subject and details relating to this are provided on consultation of the full patent text.


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