The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Aug. 24, 2023
Applicant:

Beth Israel Deaconess Medical Center, Inc., Boston, MA (US);

Inventors:

Dan H. Barouch, Newton, MA (US);

Peter Abbink, Winthrop, MA (US);

Mark Justin Iampietro, Boston, MA (US);

Menzo J. E. Havenga, Boston, MA (US);

Assignee:
Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C12N 15/861 (2006.01); A61K 31/7088 (2006.01); A61K 35/761 (2015.01); A61K 39/00 (2006.01); A61K 39/235 (2006.01); C07K 14/075 (2006.01); C07K 14/54 (2006.01);
U.S. Cl.
CPC ...
C07K 14/075 (2013.01); A61K 31/7088 (2013.01); A61K 35/761 (2013.01); A61K 39/0011 (2013.01); A61K 39/235 (2013.01); C07K 14/5425 (2013.01); C12N 15/861 (2013.01);
Abstract

Featured are recombinant adenoviruses and vectors thereof. In particular, the adenoviruses are simian (rhesus) adenoviruses having a low seroprevalence and high immunogenicity (when expressing, e.g., an antigenic polypeptide) relative to other adenoviruses and vectors thereof. Also featured are methods for producing the adenoviruses and methods of treatment of diseases by administering the adenoviral vector(s) to a subject (e.g., a human).


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