The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Feb. 28, 2024
Applicant:

Antengene Discovery Limited, Shanghai, CN;

Inventors:

Ming Zhang, Shanghai, CN;

Ya Kong, Shanghai, CN;

Lulu Jiang, Shanghai, CN;

Bin Jiang, Shanghai, CN;

Guoqiang Dai, Shanghai, CN;

Yulong He, Shanghai, CN;

Bing Hou, Shanghai, CN;

Bo Shan, Shanghai, CN;

Jay Mei, Shanghai, CN;

Assignee:
Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 487/04 (2006.01); A61K 31/4985 (2006.01); A61K 31/506 (2006.01); C07D 471/14 (2006.01); C07D 519/00 (2006.01);
U.S. Cl.
CPC ...
C07D 487/04 (2013.01); A61K 31/4985 (2013.01); A61K 31/506 (2013.01); C07D 471/14 (2013.01); C07D 519/00 (2013.01);
Abstract

The present application provides novel PRMT5 and/or MTA-cooperative PRMT5 inhibiting compounds, or pharmaceutically acceptable salts thereof. The present application also provides pharmaceutical compositions comprising one or more of the compounds, or pharmaceutically acceptable salts thereof as an active ingredient, and the use of the compounds, or pharmaceutically acceptable salts thereof in the treatment of diseases or disorders, including cancers.


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