The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Aug. 03, 2020
Applicant:

Merck Sharp & Dohme Llc., Rahway, NJ (US);

Inventors:

Stephane L. Bogen, Somerset, NJ (US);

Ping Chen, Edison, NJ (US);

Dane James Clausen, Rahway, NJ (US);

Jinsong Hao, Belle Mead, NJ (US);

Dipannita Kalyani, Union, NJ (US);

Michael T. Rudd, Collegeville, PA (US);

Shawn P. Walsh, Bridgewater, NJ (US);

Lan Wei, Berkeley Heights, NJ (US);

Dexi Yang, Livingston, NJ (US);

Assignee:

Merck Sharp & Dohme LLC, Rahway, NJ (US);

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07D 403/04 (2006.01); C07D 207/14 (2006.01); C07D 401/04 (2006.01); C07D 405/04 (2006.01); C07D 409/04 (2006.01); C07D 413/04 (2006.01); C07D 413/10 (2006.01); C07D 417/04 (2006.01); C07D 417/14 (2006.01); C07D 471/04 (2006.01); C07D 491/048 (2006.01); C07D 498/04 (2006.01);
U.S. Cl.
CPC ...
C07D 403/04 (2013.01); C07D 207/14 (2013.01); C07D 401/04 (2013.01); C07D 405/04 (2013.01); C07D 409/04 (2013.01); C07D 413/04 (2013.01); C07D 413/10 (2013.01); C07D 417/04 (2013.01); C07D 417/14 (2013.01); C07D 471/04 (2013.01); C07D 491/048 (2013.01); C07D 498/04 (2013.01);
Abstract

The present invention is directed to heteroaryl pyrrolidine and piperidine compounds which are agonists of orexin receptors. The present invention is also directed to uses of the compounds described herein in the potential treatment or prevention of neurological and psychiatric disorders and diseases in which orexin receptors are involved. The present invention is also directed to compositions comprising these compounds. The present invention is also directed to uses of these compositions in the potential prevention or treatment of such diseases in which orexin receptors are involved.


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