The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Feb. 28, 2024
Applicant:

Opus Genetics, Inc., Farmington Hills, MI (US);

Inventors:

Daniela Carmen Oniciu, Gainesville, FL (US);

Corina-Mihaela Manta, Bucharest, RO;

Anthony Carestia, Greensboro, NC (US);

Jon Housley, Summerfield, NC (US);

Assignee:

Opus Genetics, Inc., Farmington Hills, MI (US);

Attorney:
Primary Examiner:
Int. Cl.
CPC ...
C07C 57/42 (2006.01); C07C 69/88 (2006.01);
U.S. Cl.
CPC ...
C07C 57/42 (2013.01); C07C 69/88 (2013.01); C07B 2200/13 (2013.01);
Abstract

This invention relates to Compound 1 (APX3330) salts and esters. The invention also provides compositions comprising a Compound 1 salt or ester. The invention also provides compounds of formula (I) and formula (II) and pharmaceutically acceptable salts thereof. The invention further provides compositions comprising a compound of formula (I) or formula (II), or a pharmaceutically acceptable salt thereof; and a pharmaceutically acceptable carrier or vehicle. The invention also provides methods for treating or preventing a disease, such as cancer, a liver disorder, an ocular disorder, a cardiovascular disorder, fibrosis, or an inflammatory disorder, comprising administering to a subject in need thereof an effective amount of a Compound 1 salt or ester; or compound of formula (I) or formula (II), or pharmaceutically acceptable salt thereof.


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