The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Sep. 27, 2023
Applicants:

Rinuagene Biotechnology Co., Ltd., Jiangsu, CN;

Rinuagene International HK Limited, Hong Kong, CN;

Inventors:

Rui Xing, Suzhou, CN;

Kai Lv, Suzhou, CN;

Shan Cen, Suzhou, CN;

Yijie Dong, Suzhou, CN;

Attorneys:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
C07C 229/16 (2006.01); A61K 47/18 (2017.01);
U.S. Cl.
CPC ...
C07C 229/16 (2013.01); A61K 47/183 (2013.01); C07C 2601/02 (2017.05); C07C 2601/04 (2017.05);
Abstract

The present invention relates to a long chain alkyl esteramine lipid compound as shown in Formula I, preparation method therefor as well as use thereof in nucleic acid delivery, the long chain alkyl esteramine lipid compound provided by the present invention has an excellent encapsulation rate and delivery effect as a lipid molecule in delivering disease treatment or preventive agents, showing lower toxicity and certain tissue distribution characteristics, and providing a basis of more selections for delivering disease therapeutic or prophylactic agents.


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