The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.

The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.

Date of Patent:
May. 27, 2025

Filed:

Dec. 12, 2024
Applicant:

Wuxi Zhiyan Biotechnology Co., Ltd, Wuxi, CN;

Inventors:

Beilei Cai, Wuxi, CN;

Zhihui Tian, Wuxi, CN;

Yue Wang, Wuxi, CN;

Zixuan Xu, Wuxi, CN;

Shuyan Yang, Wuxi, CN;

Liyong Du, Wuxi, CN;

Jingguo Yang, Wuxi, CN;

Attorney:
Primary Examiner:
Assistant Examiner:
Int. Cl.
CPC ...
A61K 8/362 (2006.01); A61K 8/42 (2006.01); A61K 9/06 (2006.01); A61K 31/194 (2006.01); A61K 31/197 (2006.01); A61K 47/10 (2017.01); A61K 47/18 (2017.01); A61K 47/20 (2006.01); A61Q 19/00 (2006.01);
U.S. Cl.
CPC ...
A61K 8/362 (2013.01); A61K 8/42 (2013.01); A61K 9/06 (2013.01); A61K 31/194 (2013.01); A61K 31/197 (2013.01); A61K 47/10 (2013.01); A61K 47/183 (2013.01); A61K 47/20 (2013.01); A61Q 19/00 (2013.01); A61K 2800/5922 (2013.01); A61K 2800/805 (2013.01);
Abstract

Disclosed are a liquid supramolecular self-recognition system of low-pH azelaic acid, and a preparation method therefor and application thereof. The preparation method for the ternary liquid supramolecular self-recognition system of low-pH azelaic acid/succinic acid/panthenol includes the following steps: mixing and heating azelaic acid, succinic acid, and panthenol in a molar ratio of 1:0.5:1-1:10:10 in a sealed container to obtain a mixture and heated at 60-120° C. for more than 1-24 hours, and cooling down the mixture to room temperature after the heating is completed to obtain the liquid supramolecular self-recognition system of low-pH azelaic acid. The preparation method is green and simple, and the resulting supramolecular self-recognition system can effectively improve the solubility of azelaic acid, and have excellent stability without precipitation. In addition, the supramolecular self-recognition system for the azelaic acid/succinic acid/panthenol prepared in the present disclosure is in a liquid form, and can be directly applied to subsequent formulations without special treatment.


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