The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
Aug. 22, 2023
Applicant:
Nantcell, Inc., Culver City, CA (US);
Inventor:
Kayvan Niazi, Culver City, CA (US);
Assignee:
NantCell, Inc., Culver City, CA (US);
Attorneys:
Primary Examiner:
Int. Cl.
CPC ...
A61K 39/00 (2006.01); A61K 39/39 (2006.01); A61P 35/00 (2006.01); C07K 14/705 (2006.01); C12N 15/70 (2006.01); C12N 15/81 (2006.01); C12N 15/861 (2006.01);
U.S. Cl.
CPC ...
A61K 39/001102 (2018.08); A61K 39/0011 (2013.01); A61K 39/39 (2013.01); A61P 35/00 (2018.01); C07K 14/70596 (2013.01); C12N 15/70 (2013.01); C12N 15/81 (2013.01); C12N 15/861 (2013.01); A61K 2039/51 (2013.01); A61K 2039/523 (2013.01); A61K 2039/5256 (2013.01); A61K 2039/53 (2013.01); A61K 2039/585 (2013.01); C12N 2710/10011 (2013.01); C12N 2710/10021 (2013.01); C12N 2710/10043 (2013.01); C12N 2799/022 (2013.01);
Abstract
Systems and methods are presented that allow for selection of tumor neoepitopes that are then used to generate recombinant nucleic acids that encode one or more polytopes that are optimized for proper trafficking and processing. In preferred methods, the polytopes are encoded in a plasmid and/or a viral expression system for use as a therapeutic agent.