The patent badge is an abbreviated version of the USPTO patent document. The patent badge does contain a link to the full patent document.
The patent badge is an abbreviated version of the USPTO patent document. The patent badge covers the following: Patent number, Date patent was issued, Date patent was filed, Title of the patent, Applicant, Inventor, Assignee, Attorney firm, Primary examiner, Assistant examiner, CPCs, and Abstract. The patent badge does contain a link to the full patent document (in Adobe Acrobat format, aka pdf). To download or print any patent click here.
Patent No.:
Date of Patent:
May. 27, 2025
Filed:
Aug. 15, 2022
Applicant:
Turning Point Therapeutics, Inc., Princeton, NJ (US);
Inventors:
Jingrong J. Cui, Princeton, NJ (US);
Yishan Li, Princeton, NJ (US);
Evan W. Rogers, Princeton, NJ (US);
Dayong Zhai, Princeton, NJ (US);
Wei Deng, Princeton, NJ (US);
Zhongdong Huang, Princeton, NJ (US);
Assignee:
Turning Point Therapeutics, Inc., Princeton, NJ (US);
Primary Examiner:
Int. Cl.
CPC ...
A61K 31/519 (2006.01); A61P 35/00 (2006.01);
U.S. Cl.
CPC ...
A61K 31/519 (2013.01); A61P 35/00 (2018.01);
Abstract
This disclosure relates to the use of certain diaryl macrocycle compounds, specifically (7S13R)-11-fluoro-7,13-di-methyl-6,7,13,14-tetrahydro-1,15-ethenopyrazolo[4,3-f][1,4,8,10]benzoxatriazacyclotridecin-4(5H)-one in the treatment of disease in mammals. This disclosure also relates to compositions including such compounds, and to methods of using such compositions in the treatment of diseases in mammals, especially in humans.